CORDIS Project
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This project investigates the evolutionary interactions between bacteria and their viruses, known as bacteriophages. It aims to identify and validate the counter-defense mechanisms of phages using advanced genomic and proteomic techniques, enhancing our understanding of microbial immunity and evolutionary biology.
Tight co-evolutionary interactions of bacteria and their viruses, termed bacteriophages or phages, lead to continuous selection towards adaptation of the host and counter-adaptations of the parasite.
Studying this evolutionary arms race resulted in discovering multiple sophisticated defense mechanisms of bacteria, such as CRISPR-Cas and restriction-modification systems.
However, the diversity and mechanisms of action of counter-defense strategies of phages remain largely unknown.
In this proposa…
UNIVERSITAT WIEN
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