CORDIS Project
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This project investigates the interactions between bacteriophages and bacteria to understand how phages can overcome bacterial defenses. By studying specific phage mechanisms, it aims to develop new antimicrobial therapies that target bacterial stress responses, enhancing treatment options for infections.
Bacteriophages, viruses of bacteria, are the most abundant life form on Earth.
The prospect of using them in the fight against pathogenic bacteria has long been recognised, but their very high specificity and unpredictable reproduction limits their use in medicine.
The mechanisms phages use to fight bacteria are attractive candidates for the development of novel antimicrobial applications, but are still very poorly understood.
Indirect evidence exists of toxin antitoxin systems (TAS) and stringe…
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