CORDIS Project
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This project investigates the role of type A pericytes in forming the stroma of tumors, aiming to understand their contribution to cancer progression. By studying these cells in glioblastoma models, the research seeks to identify potential therapeutic targets to impede tumor growth.
Cancer is a devastating diagnosis since treatments to prevent a lethal outcome are limited.
Tumor constitutes a complex tissue consisting of malignant cells and stromal cells.
Emerging studies have shown the importance of stroma in tumor growth, invasion, and metastasis highlighting its potential as an attractive target for cancer therapy.
However, the source of tumor stroma generating cells remains elusive.
Generation of connective tissue is a general feature of scarring and fibrosis.
While sca…
KAROLINSKA INSTITUTET
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