CORDIS Project
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This project aims to create a microfluidic device that mimics multiple organs to study drug absorption and toxicity. By integrating electrodes for real-time measurements, the device will enhance drug development processes and improve understanding of drug-induced organ toxicity.
PORTable STaNDOuTs aims to develop a multiple Organs-on-a-Chip (MOOC) microfluidic device integrated with electrodes for carrying out Transepithelial electrical resistance (TEER) measurements.
The key motivation for adopting such an approach is to develop a rapid, versatile and cost-effective prototype with ability for real-time monitoring to replace the conventional long and cost-ineffective preclinical procedures involved in the drug development process.
On administration of an oral pharmaceut…
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