CORDIS Project
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This project explores the potential of photodynamic therapy to induce immunogenic cell death in head and neck cancers. By enhancing the immune response through tumor-associated antigens, it aims to improve treatment outcomes for patients.
Immunogenic cell death (ICD) is a regulated cell death that stimulates the immune responses resulting in the establishment of long- term immunological memory. ICD alert the immune system by tumor-associated antigens and tumor neoantigens (i.e., antigenicity) and releasing immunostimulant mediators such as the damage- associated molecular patterns (DAMPs, adjuvanticity). ICD can be efficiently induced by photodynamic therapy (PDT).
Our key hypothesis is that PDT based on clinically approved and i…
UNIVERSITEIT GENT
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