CORDIS Project
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This project seeks to uncover the cellular mechanisms behind protein aggregation and toxicity in neurodegenerative diseases, particularly Alzheimer's disease. By studying a specific protein modifier, it aims to identify new therapeutic targets to mitigate age-related neurodegenerative conditions.
The worldwide aging population will lead to a dramatic increase in the number of people with Alzheimer’s disease and other incurable age-related neurodegenerative diseases over the next few decades.
By 2050 over 115 million are expected to suffer from these devastating diseases.
The major pathological hallmark of these disorders is the accumulation of aggregation-prone disease proteins in aggregates in the brain.
To understand the disease mechanisms and to identify targets for treatment, I aim t…
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
ACADEMISCH ZIEKENHUIS GRONINGEN
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