CORDIS Project
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This project investigates how pancreatic cancer cells interact with their surrounding environment to promote metastasis, particularly focusing on the role of specific signaling molecules. By studying these interactions, the project aims to identify potential targets for therapies that could prevent the spread of cancer…
More than 50% of all pancreatic cancer patients suffer of metastasis either at the time of diagnosis or as recurrent disease after therapy.
During metastatic dissemination, cancer (stem) cells shed into the blood stream and seed the liver as isolated entities.
Genetic alterations underlying these processes have not been identified thus far.
Therefore, it is currently not possible to discriminate which patients are at higher risk of developing metastasis or to design targeted therapies to prevent…
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