CORDIS Project
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This project explores how proteins interact within crowded cellular environments, focusing on the concept of dynamical sorting. It aims to develop advanced simulation techniques to better understand molecular interactions critical for cellular function.
Biological cellular function relies on the coordination of many information processing steps in which specific biomolecular complexes are formed.
But how can proteins and ligands find their targets in extremely crowded cellular membranes or cytosol?
Here, I propose that intracellular signal processing depends upon the spatiotemporal order of molecules arising from “dynamical sorting”, i.e. no stable structure may exist at any time and yet the molecules might be ordered at all times. I propose to…
FREIE UNIVERSITAET BERLIN
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