CORDIS Project
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This research investigates the role of specific lipid kinases in prostate cancer biology, focusing on their influence on the androgen receptor pathway. The study aims to create a prostate-specific knockout model to better understand these kinases' functions and their potential as drug targets.
As a result of it’s specialized secretory functions, the prostate has a unique biology that makes it prone to the development of cancer.
Specifically, a strong dependence on hormonal stimulation through the androgen receptor (AR) pathway that is implicated in driving downstream changes to the central metabolism of the cell.
To find answers to clinical questions, I am delving into the fundamental mechanisms of a previously overlooked family of lipid kinases.
The type II phosphatidylinositol-5-pho…
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