CORDIS Project
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This project investigates the formation and dynamics of cytoplasmic granules, specifically processing bodies, under endoplasmic reticulum and mitochondrial/lysosomal stresses. It aims to understand how these granules respond to various stressors and their role in cellular recovery, using advanced techniques like mass s…
One of the first responses to eukaryotic cellular stress is the formation of cytoplasmic granules like processing bodies (PBs) and stress granules (SGs). PBs are membrane-less structures that are dynamic in their assembly/disassembly and composition depending on the type of stress that they encounter.
While glucose starvation is the main stress applied to study PB formation and dynamics, much less is known about PBs under other stresses, especially endoplasmic reticulum (ER) and mitochondrial/ly…
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