CORDIS Project
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This research investigates the role of the Pax6 transcription factor in mouse brain development, particularly its interactions with the Shh pathway. The study aims to clarify gene expression changes and their implications for understanding neurodevelopmental disorders.
Forebrain development is an extremely complex process that depends on the coordination of multiple molecular networks controlled by a relatively small group of transcription factors.
Understanding of these genes, their downstream pathways and their spatial and temporal interactions is still far from clear, seriously limiting our knowledge of the molecular mechanisms of brain development and the causes of neurodevelopmental diseases.
Our research will be aimed at deepening understanding of the mo…
THE UNIVERSITY OF EDINBURGH
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