CORDIS Project
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This project investigates the biology of Plasmodium parasites during the liver stage of malaria infection. By studying DNA replication and damage, it aims to understand how these factors contribute to genetic diversity and virulence, ultimately informing new strategies for malaria intervention.
A world free of malaria is certainly a desirable goal.
However, in spite of the significant incidence reduction achieved globally between 2000-2015, malaria still kills a child every minute.
The limited understanding of Plasmodium’s biology hampers the development of novel intervention strategies.
Upon transmission by Anopheles mosquitos, Plasmodium parasites must reach the liver and infect hepatocytes.
Inside a hepatocyte, each parasite replicates into thousands of new erythrocyte-infectious fo…
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