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The PAMFGAL project investigates the molecular functions of Polycomb Repressive Complex 2 in green algae to understand its ancestral roles in cellular identity and development. It employs advanced techniques like sequencing and microscopy to analyze histone modifications and PRC2 activity, aiming to enhance ingredient…
Polycomb-group (PcG) proteins assemble into complexes to maintain cellular identity in multicellular organisms and regulate phase transitions in plants by epigenetic gene repression.
Polycomb Repressive Complex 2 (PRC2) is one of the complexes that is evolutionary conserved and catalyzes trimethylation of histone H3 on lysine 27 (H3K27me3). PRC2 is extensively studied in flowering plants, where it determines cell fate during development.
Reports predicts putative homologs of PRC2 subunits encode…
BIOLOGICKE CENTRUM AKADEMIE VID CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE
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