CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of the p73 protein in cancer, particularly its potential oncogenic functions in tumors. By identifying factors that enable cancer cells to thrive with high p73 levels, the project aims to develop targeted therapies that can reactivate p73's tumor suppressor functions.
p73 is a transcription factor of the p53 tumor suppressor family.
In approximately 50% of all cancer patientsthe tumor suppressor function of p53 is irreversibly disabled by point mutations, which makes p53 one of themost frequently mutated genes in cancer.
This is entirely different for p73 and much of my previous work inthis field has been devoted to research on the role of p73 in cancer.In sharp contrast to p53, p73 is often highly expressed in its wild-type form in solid tumors compared toth…
PHILIPPS UNIVERSITAET MARBURG
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
