CORDIS Project
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This project investigates the role of the p53 transcription factor in Drosophila, focusing on its functions in cell adhesion, polarity maintenance, and alternative splicing. It aims to enhance understanding of p53's contributions to development and its implications for disorders related to cell death regulation.
Apoptosis is a form of cell death ubiquitously used in animals, which participates in development and in the adult in defense against potentially dangerous cells.
Not surprisingly, deregulation of cell death has severe consequences for the developing organism and adult.
Inappropriate cell death is associated with many disorders including degenerative neurological diseases (excess of cell death) and cancer (loss of cell death).
One of the important components of the cell death machinery is the p5…
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