CORDIS Project
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This project utilizes bioorthogonal click chemistry to attach magnetic nanoparticles to cell surfaces, aiming to improve magnetic hyperthermia therapy. It investigates how the location of nanoparticles affects their heating behavior and impacts cellular signaling.
The MSC OUTstandINg project will use bioorthogonal click chemistry as tool to covalently attach magnetic nanoparticles (MNPs) to living cell surfaces with the aim to address two fundamental questions in the field of magnetic hyperthermia
therapy using MNPs: 1) how the subcellular localization (on the plasma membrane or inside the cells) of MNPs affects their heating behaviour when compared to MNPs in solution 2) how MNPs immobilization and sub-lethal magnetic hyperthermia
impact different subcel…
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