CORDIS Project
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This project aims to enhance the identification and quantification of protein isoforms using a novel mass spectrometry data analysis strategy. By developing deep neural networks to predict unique molecular fingerprints, the project seeks to unlock the potential of existing proteomic data, ultimately advancing our under…
Did you know that ~80% of all proteomic data is not utilized?
Proteins play a vital role in all biological processes and organisms.
We believe that different versions of a single gene product – protein isoforms – shape the molecular diversity of life.
However, comprehensive evidence on protein-level is not available.
Chromatography-coupled tandem mass spectrometry (LC-MS/MS) is the de-facto standard for measuring proteomes, but it is not good at identifying isoforms because at least 80% of the r…
TECHNISCHE UNIVERSITAET MUENCHEN
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