CORDIS Project
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The ORIgAMI project investigates the role of Immunoglobulin A (IgA) in the immune response to respiratory viruses like influenza. By studying the behavior of IgA-producing B cells, the project aims to enhance vaccine design to improve protection against airborne pathogens.
Several times in human history, we faced sudden outbreaks of respiratory viruses that rapidly spread over the world before we could design broadly protective vaccines.
Such was the case of the H1N1 influenza virus that killed 50 million people during the 1918 Spanish flu and SARS-CoV-2 that led to at least 5 million deaths during the current COVID-19 pandemics.
Influenza and SARS-CoV-2 elicit robust humoral immune responses, including production of virus-specific antibodies of the IgM, IgG, and…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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