CORDIS Project
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ORGESTRA aims to develop personalized disease models for cystic fibrosis and cystinosis using stem cell-derived organoids. The project trains doctoral candidates to identify treatment strategies and facilitate the transition of research findings to clinical applications.
The vast majority of rare diseases are characterized by genetic origin, often severe in pathology and with limited or no treatment options.
This also includes the paediatric disorders cystic fibrosis (CF) and cystinosis.
Both diseases usually manifest in the first year of life.
In recent year, great progress has been made in CF research allowing a swift transfer of novel drugs from bench to bedside.
This is fueled by the application of advanced in vitro models, viz. organoids, in phenotyping pat…
UNIVERSITEIT UTRECHT
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Netherlands, Utrecht
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Belgium, Leuven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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