CORDIS Project
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This project focuses on enhancing a gene therapy approach for cancer using non-pathogenic bacteria. The research aims to improve the delivery of therapeutic genes specifically to tumors through oral administration, leveraging the unique properties of gut bacteria.
Background:
The applicant has generated a body of research work in the field of gene therapy for cancer.
Our recent research has shown that oral administration of Bifidobacteria to mice results in translocation from the Gastro-Intestinal Tract (GIT) with subsequent homing to and replication specifically in tumours, providing high-level gene expression confined to tumours.
These findings indicate potential for treatment and/or detection of cancer via ingestion of non-pathogenic bacteria.
We have…
UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
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