CORDIS Project
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This project focuses on developing an innovative optical method to selectively activate a specific subtype of glutamate receptors in the brain. By using light-sensitive compounds, the research aims to enhance our understanding of these receptors' roles in synaptic function and their potential therapeutic applications i…
NMDA receptors (NMDARs) form a class of receptors gated by glutamate, the major neurotransmitter in the mammalian brain.
These receptors play fundamental roles in synaptic transmission and plasticity.
They are also involved in numerous pathologies including stroke, mental retardation or schizophrenia. NMDARs are thus targets of strong therapeutic interest. NMDARs are tetramers usually composed of two GluN1 and two GluN2 subunits encoded by four different genes (GluN2A-D), resulting in a large nu…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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France, Paris
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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