CORDIS Project
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The project aims to enhance understanding of cardiac electrical conduction following myocardial infarction. It combines innovative imaging techniques to study heart tissue in three dimensions, focusing on how structural changes impact heart rhythms.
Myocardial infarction (MI) is a key risk factor for sudden cardiac death, a leading global cause of mortality.
Understanding how altered tissue architecture in MI influences cardiac electrical conduction is crucial to develop therapies which treat abnormal heart rhythms (arrhythmias) clinically.
Optical measurement of transmembrane voltage in cardiac muscle is a versatile, non-invasive tool to investigate myocardial conduction.
However, the current techniques of wide-field and multiphoton imagin…
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