CORDIS Project
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This project explores the mechanisms of deep brain stimulation (DBS) for treating neurological disorders. By using advanced optical techniques to measure neuronal activity in awake animals, it aims to clarify how DBS affects brain circuits and improve therapeutic protocols for epilepsy.
Deep brain stimulation (DBS) is a promising neuromodulation technique for the treatment of neurological and psychiatric diseases. DBS electrically stimulates brain tissue via implanted electrodes.
However, the biophysical and therapeutic mechanisms underlying DBS remain largely unknown.
While long-standing theories suggest that DBS suppresses neurons, subsequent studies have shown that DBS activates neurons via direct axonal excitation modulating membrane dynamics, information transfer, and netw…
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
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