CORDIS Project
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This project focuses on developing advanced mass spectrometry techniques to analyze vitamin D metabolism in blood and tissues. By creating new methods to measure various vitamin D metabolites, the project aims to improve our understanding of vitamin D's role in human health and its bioavailability.
Vitamin D has well-recognised actions on the skeleton, but also exerts potent effects on extra-skeletal tissues.
Current approaches to measure vitamin D almost exclusively rely on measuring a single, inactive vitamin D metabolite – 25-hydroxyvitamin D.
However, vitamin D undergoes complex metabolism that may strongly influence the physiological impact of vitamin D.
This is particularly important for extra-skeletal responses to vitamin D, where tissue-specific metabolites appear to be a crucial c…
THE UNIVERSITY OF BIRMINGHAM
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