CORDIS Project
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This project aims to enhance cerebral protection during transcatheter aortic valve implantation by optimizing cerebral embolic protection devices. It utilizes advanced computational modeling to improve device design against particle-laden turbulent flow in the aorta.
Transcatheter aortic valve implantation (TAVI) has quickly become the clinical standard for patients with medium to high risk for surgery.
Despite being a promising treatment for aortic valve disease in the elderly, stroke remains a major complication of TAVI.
Large randomized clinical trials reported stroke within 30 days in 5-7% of the patients undergoing TAVI . TCD ultrasound imaging has showed cerebral embolic signals in 100% of the TAVI patients, mainly during valve deployment.
Cerebral emb…
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