CORDIS Project
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This project explores the role of osteopontin in allergic asthma, focusing on its effects on immune responses. It aims to clarify how osteopontin influences dendritic cells and T cell interactions during allergic reactions, potentially leading to new therapeutic strategies.
In allergic asthma, an important health problem, disease is driven by allergen-specific Th2 immune responses.
Differentiation of Th2 cells depends on their early interactions with antigen presenting cells, such as dendritic cells (DCs), and cytokines are crucial for this process.
Osteopontin (Opn) was originally identified as an important cytokine for Th1 immunity and autoimmunity.
Our group recently demonstrated that Opn is highly expressed in the lungs of asthmatic patients and of mice with Th…
BIOMEDICAL RESEARCH FOUNDATION, ACADEMY OF ATHENS
IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON
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