CORDIS Project
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The OnTarget project aims to develop innovative tools to study how proteins are directed to specific organelles within cells. By uncovering missing targeting pathways and creating techniques to analyze cargo delivery under varying conditions, the project seeks to enhance our understanding of cellular processes and impr…
Half of eukaryotic proteins require targeting to specific organelles to execute their function.
Research from multiple labs, including our own, has uncovered some of the pathways that recognize such cargo proteins and target them in an efficient and regulated fashion.
However, many central pathways are clearly still missing.
Importantly, current studies tend to focus on single cargo proteins and how they utilize one particular targeting pathway, creating an over-simplified view of the cellular r…
WEIZMANN INSTITUTE OF SCIENCE
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