CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project focuses on understanding how mutations in oncoproteins disrupt protein interactions and signaling pathways in cancer cells. By employing proteomics and computational methods, the research aims to identify new therapeutic targets and improve the understanding of cancer biology.
The inappropriate activity of signaling pathways and activation of gene-expression programs is a primary driver of transformation in cancer cells.
In turn, dis-regulation of signaling pathways in cancer cells is frequently caused by mutations in important oncoproteins, which may alter protein expression, structure or function.
In addition, increasing evidence shows that oncoprotein mutations may alter the interactions of oncoproteins with other proteins, causing wide-spread perturbations to the…
UNIVERSITY OF SOUTHAMPTON
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
