CORDIS Project
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This project investigates the role of the OIT3 gene in magnesium handling within the kidneys. It aims to uncover mechanisms of magnesium homeostasis and identify potential clinical applications related to magnesium disturbances and kidney diseases.
Mg2+ is the second most abundant intracellular cation after potassium and it plays an essential role in the human body.
The kidney is the key organ regulating Mg2+ homeostasis through complex processes of excretion and reabsorption.
This takes place in the nephrons, the functional units of the kidney, via paracellular mechanisms and ion transporters.
Alterations in Mg2+ homeostasis are associated with several diseases and vice versa.
Hypomagnesemia (serum Mg2+ <0.70 mmol/L) is the most common fo…
STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
THE JACKSON LABORATORY NON PROFIT CORPORATION
United States, Bar Harbor
Type: Other
Activity type: Other
SME: No
STICHTING RADBOUD UNIVERSITEIT
Netherlands, Nijmegen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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