CORDIS Project
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This project explores the role of the Salt-inducible kinase 3 gene in regulating energy balance and its potential as a target for obesity treatment. It involves creating specific mouse models to study the gene's effects on metabolism and sleep.
In the last decades, obesity has become a growing health burden hence the importance of understanding its pathophysiology and the need to search for new therapeutic targets.
Yanagisawa/Funato Lab (Y/F Lab) has recently discover that a splicing mutation in the Salt-inducible kinase 3 (Sik3) gene is involved in determining sleep need , and as well in a likely defective energy homeostasis since mice mutant for exon 13 of the Sik3 gene present an obese phenotype.
The main objective of my proposed ac…
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
UNIVERSIDAD DE SANTIAGO DE COMPOSTELA
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Japan, Tsukuba Ibaraki
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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