CORDIS Project
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This project investigates how dietary nutrients influence the immune system at mucosal surfaces, particularly focusing on the aryl hydrocarbon receptor's role in regulating immune cell development. It aims to link nutrition with immune responses to improve health outcomes.
The last decade has witnessed an explosion of research into the molecular networks ensuring maintenance of a mutualistic relationship between microbes and host cell networks at mucosal surfaces.
Failure of such homeostatic or adaptive programs lead to susceptibility to intestinal infections or to chronic inflammation causing debilitating human diseases such as inflammatory bowel diseases or inflammation-induced intestinal cancer.
In contrast to the role of the microbiota and its composition, the…
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