CORDIS Project
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This project investigates the role of the Nrf2 transcription factor in vascular health under diabetic conditions. By studying its impact on oxidative stress and inflammation, the research aims to uncover mechanisms that contribute to vascular dysfunction in diabetes.
Vascular diseases represent the main cause of disability and mortality linked with long-term diabetes mellitus, a metabolic disease affecting around 20% of total world population.
Diabetic vessels undergo both functional and structural changes, rendering them prone to cardiovascular pathology, including atherosclerosis, hypertension or myocardial infarction.
Hyperglycemia, together with inflammation, play a key role by altering cell metabolism and different signal transduction pathways in vascul…
UNIVERSIDAD AUTONOMA DE MADRID
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