CORDIS Project
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The project aims to develop new synthetic methods for complex natural products by studying the biosynthesis of ambruticin and jerangolid. It focuses on utilizing specific enzymes as biocatalysts to enhance the efficiency of chemical synthesis processes.
The aim of the project is to translate the knowledge from biosynthetic pathways of natural products into Organic Chemistry, achieved by developing novel chemoenzymatic total syntheses of the polyketide natural products ambruticin and jerangolid.
In both biosynthetic pathways, large parts of the molecular complexity are set up by tailoring enzymes.
These enzymes will be studied regarding their potential to act as biocatalysts that can substitute late and crucial steps in total syntheses.The proje…
GOTTFRIED WILHELM LEIBNIZ UNIVERSITAET HANNOVER
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