CORDIS Project
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This project focuses on discovering new therapies for visceral leishmaniasis and Chagas disease by exploring natural product-derived alkaloids. It aims to identify novel drug candidates with fewer side effects and enhanced efficacy against these parasitic diseases.
The development of new therapies for leishmaniases (which affeThe development of new therapies for visceral leishmaniasis (affects ~12 million people worldwide) and Chagas disease (~6-7 million people worldwide) is critically dependent on the identification of novel pharmacophores with new modes of action.
Current treatments suffer from severe side effects, high cost, patient compliance issues, and emerging resistance; as such, new therapeutic leads are urgently required.
Despite significant inv…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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