CORDIS Project
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This project investigates the role of Drosophila neurotrophins in structural plasticity and neurodegeneration. By studying the fruit fly's brain, the research aims to define neural circuits, cellular events, and the impact of neurotrophin loss on brain function and aging.
The brain undergoes structural changes in response to experience, known as structural plasticity.
Loss of plasticity most likely underlies brain changes associated with aging and neurodegeneration.
Neurotrophins (NTs) are the main proteins linking structure and function in the human brain.
Lack of NTs underlies neurodegeneration and NTs are the favored factors to promote nervous system repair.
How NTs implement these functions, and how alterations in NT function lead to neurodegeneration, is not…
THE UNIVERSITY OF BIRMINGHAM
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