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NOVOFLAT aims to develop a method for creating sp3–sp3 carbon bonds using a triple catalytic cascade. This innovative approach allows for precise control over bond formation, with minimal waste, facilitating the synthesis of complex molecules for drug discovery and other applications in molecular sciences.
Although cross-coupling reactions have become one of the pillars of modern chemical synthesis, the ability to forge sp3–sp3 bonds with improved flexibility, practicality, predictable site-selectivity, preparative utility, stereocontrol and with nearly zero-generation of waste has eluded chemists for decades, remaining a major challenge and an uncharted cartography in catalytic endeavours.
The successful realization of this goal will represent a paradigm shift from the standard logic of organic s…
FUNDACION PRIVADA INSITUTO CATALAN DE INVESTIGACION QUIMICA ICIQ
FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA
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