CORDIS Project
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This project develops a high-throughput method for creating gene-corrected blood-forming stem cells and CAR T cells using a novel gene delivery technology. By optimizing photoporation and CRISPR gene editing, it aims to streamline production and enhance the clinical application of cell therapies.
Despite the increasing awareness that cell and gene-therapy approaches have tremendous biomedical potential, their broad clinical application has been challenging due to prolonged and expensive production times and the emergence of severe immune- and gene-delivery dependent side effects.
In this proposal, we aim to establish a stream-lined and high-throughput protocol for iPSC-based cell therapy by combining a novel technological platform for gene delivery with a breakthrough biological concept…
UNIVERSITEIT GENT
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Belgium, GENT
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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