CORDIS Project
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This project investigates a newly discovered non-ionic signaling mechanism in NMDA receptors, which play a crucial role in synaptic plasticity related to learning and memory. By using advanced imaging and electrophysiology techniques, it aims to redefine our understanding of synaptic signaling in the brain's cortex.
Long-term synaptic plasticity is an experience dependent increase or decrease in synaptic signaling between nerve cells that can last from hours to days or even longer.
It is thought to represent the cellular substrate of learning and memory by providing an information storage mechanism in the brain.
At many excitatory synapses, plasticity-induction processes involve NMDA receptors, glutamate-gated ion channels. I recently discovered a new form of NMDA receptor signaling during spike-timing depe…
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
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