CORDIS Project
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This project aims to develop a more efficient, fully synthetic method for producing noroxymorphone, a key compound in opioid medications. By reducing reliance on poppy cultivation, it seeks to create a sustainable and industrially viable synthesis pathway.
Opiates, derived from the poppy plant and exemplified by morphine, are important medicines for pain and other disorders because of their agonistic action on the opioid receptors.
However, many opiates have bad side effects such as respiratory depression, sedation, and constipation.
They can be highly addictive, which leads to abuse and overdose deaths.
To address these issues, “nal-compounds” have been developed, which attenuate the effects of opioid receptor agonists, making them useful for tre…
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