CORDIS Project
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This project investigates the regulation of the mTOR complex 1, a key player in cell growth and metabolism, particularly in response to amino acids. It aims to uncover Rag-independent mechanisms of mTORC1 activation, which could lead to new drug targets for related diseases.
The mTOR complex 1 (mTORC1) is a master regulator of cell growth and metabolism in response to environmental cues, such as nutrients.
Its dysregulation is a common feature of several life-threatening disorders, including cancer and metabolic disease.
Therefore, understanding how mTORC1 is regulated is of great importance for both basic and translational research.The availability of Amino Acids (AA) is a prerequisite for cell growth, hence a robust mTORC1 regulator.
Previous studies on how AA reg…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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