CORDIS Project
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This project explores the biosynthetic potential of microorganisms, particularly focusing on radical SAM enzymes that catalyze unique biochemical reactions. It aims to develop new synthetic biology approaches to create novel chemicals with beneficial properties by understanding these enzymes' mechanisms.
Natural products are a constant source of inspiration in chemistry and have played a key role in the development of medicine.
Recently, thanks to the progress in genomics and metagenomics, it has appeared that the biosynthetic potential of microorganisms and the complexity of the reactions catalyzed have been largely underestimated.
Notably, enzymes using radical-based chemistry have been shown to be present in a very-large amount of biosynthetic pathways and to be widely distributed among all l…
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
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