CORDIS Project
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This project aims to identify a novel metabolic pathway linked to cancer, which includes previously unknown metabolites. By combining biochemical and genetic techniques, it seeks to explore this pathway's role in cancer development and potential therapeutic applications.
Metabolic adaptations in central carbon metabolism play a key role in cancer.
Yet, the success of therapeutic interventions in major pathways has been limited, although some of the changes have been known to exist for almost 100 years.
Biochemical textbooks present intermediary metabolism as something canonical, and the molecular identity of most enzymes required for the production of known intermediary metabolites is indeed known.
Yet, the function of many putative enzymes is still unknown, ind…
UNIVERSITE CATHOLIQUE DE LOUVAIN
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