CORDIS Project
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This project investigates the relationships between amyloid-β, tau proteins, and neurodegeneration in Alzheimer's disease using advanced imaging techniques. It aims to understand how these factors interact in the human brain, potentially leading to better treatment strategies for this neurodegenerative condition.
Alzheimer’s disease (AD) is a highly prevalent neurodegenerative disease associated with gradual loss of cognitive functions and brain vitality.
The leading “amyloid cascade” hypothesis for the pathogenesis of AD states that amyloid-β (Aβ) starts to accumulate ~15 years before symptom onset and starts a cascade of pathological events, including aggregation of tau.
It is known (mainly from post-mortem and animal studies) that these proteins may cause disruptions in brain networks, neurodegenerati…
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Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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