CORDIS Project
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This project investigates the effects of non-coding regulatory elements on neurodegenerative diseases like glaucoma and Alzheimer's. By utilizing advanced techniques, it aims to quantify these elements in specific cell types, enhancing understanding of their role in disease mechanisms.
I here propose a strategy to investigate cell type-specific effects of non-coding regulatory elements, which have been shown to play a fundamental role during the molecular pathophysiology of complex neurodegenerative diseases such as glaucoma in the eye or Alzheimer's or Parkinson's in the brain.
By leveraging techniques from various scientific disciplines such as synthetic biology, next-generation-sequencing and bioinformatics, a system will be designed that is capable of quantifying thousands…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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