CORDIS Project
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This project focuses on developing a gold nanoparticle-based drug delivery system that utilizes tailored nanoparticles, cleavable linkers, and platinum-based drugs for targeted cancer treatment. The system aims to achieve tumor-specific drug release through protease-cleavable peptides and photolabile linkers, enhancing…
The aim of the proposed research is to develop a new (Au-NP) gold nanoparticle-based drug delivery systems.
For this new synthetic approach, three different components are designed; namely, new tailored gold nanoparticle, cleavable linkers, and new platinum-based drugs.The first component is a new tailored Au-NP, which will be synthesized using a multidentate thioether “coating ligand”.
Unlike the gold nanoparticle-based nanocarriers used till date, this novel nanomaterial enables accurate funct…
UNIVERSITEIT UTRECHT
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