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The NoBiasFluors project aims to develop new fluorescent dyes for drug imaging that do not interfere with the drugs' properties. This innovation seeks to enhance the safety and effectiveness of optical imaging techniques in drug discovery.
Imaging of distribution of drugs in mice delivers accurate information for confirmation that the mechanism of action elaborated in cell-based assays is also operative in vivo.
These data are critical for the transfer of drug discovery process from pre-clinical to clinical phase.
To enable the imaging, drugs should be labeled with easily detectable moieties, e.g. radioactive markers and fluorescent dyes.
Ideally, the markers should not affect in vivo properties of the drugs that can be better ach…
FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
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LIMITED LIABILITY SCIENTIFIC SERVICE COMPANY OTAVA
Ukraine, Kyiv
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
NAUKOVO VYROBNICHYJ KOOPERATYV LECTINOTEST
Ukraine, Lviv
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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