CORDIS Project
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This project aims to extend nuclear magnetic resonance (NMR) techniques to study large protein complexes. By using advanced labeling and NMR methods, it seeks to uncover the dynamics and interactions of proteins involved in RNA processing and ion transport.
Dynamic properties of proteins are essential for their function. NMR can reveal protein dynamics in solution on a broad range of timescales and at atomic resolution.
However, NMR studies of large proteins remain challenging since conventional NMR methods are constrained to small proteins.
The aim of this project is to extend the NMR size limit to large protein complexes by combining recent developments in site-specific labeling schemes with novel NMR methods employing state-of-the-art spectromet…
UNIVERSITAET REGENSBURG
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