CORDIS Project
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This project develops a dynamic causal model to analyze NMDA receptor dynamics in the brain, aiming to understand its role in schizophrenia. By profiling receptor dysfunctions, it seeks to enhance personalized treatment strategies for patients, ultimately improving clinical outcomes through tailored interventions.
The richness of chemical signalling in the brain supports the flexible neural dynamics required for adaptive behaviour.
The NMDA receptor, one of the most ubiquitous receptors in the brain, controls synaptic plasticity and mediates learning and memory formation.
Its dysfunction is theorised to be one of the mechanisms of schizophrenia.
Profiling the changes and dysfunctions of ion channel receptors can elucidate the biological substrate of functional brain impairments and facilitate individual p…
NATIONAL INSTITUTE OF MENTAL HEALTH
NARODNI USTAV DUSEVNIHO ZDRAVI
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