CORDIS Project
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This project investigates the complex regulation of NMDA receptors in the brain, focusing on their structural dynamics and physiological roles. It aims to develop innovative tools for studying these receptors to enhance understanding of neuronal communication.
NMDA receptors (NMDARs) have long fascinated neuroscientists with their distinct biophysical properties and critical roles in neuronal communication and plasticity.
Recent studies have revealed that these glutamate-gated ion channels are more complex than initially thought, undergoing tight subunit-specific regulation by an array of endogenous modulators and existing as multiple subtypes, each with its own anatomical, functional and signaling properties.
Such complexity raises key questions rega…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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