CORDIS Project
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This project aims to understand the role of natural killer T cells in regulating intestinal immunity. It will investigate how these cells interact with the microbiota and contribute to inflammatory bowel diseases.
The mammalian intestine is colonized by trillions of microorganisms that are critical for the establishment of tissue homeostasis.
Consequently, the immune system has developed strategies to maintain a mutualistic relation with the microbiota while stopping microbial spread.
However, inappropriate function of the immune cells and/or alteration of the commensal composition can lead to inflammatory and autoimmune diseases, like inflammatory bowel disease.Among the components of the intestinal immu…
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